Rabid dog, Middle Ages, Wikimedia |
We get this word from the Latin rabidus, from rabere, to
be mad. This word also gave us rabies, first used in 1661, according to the
OED, and used to indicate an animal suffering from what was otherwise called
canine madness or hydrophobia.
The disease itself was known in ancient
Mesopotamia, where in 3000 BC, the city of Eshnuna had a law, setting out the
punishment for a person who allowed a mad dog to escape and bite somebody. Rabies is peculiar, because most diseases, after 5000 years, are much less
harmful, but rabies seems to manage without changing.
The cause of rabies is a small RNA virus, with just five
genes. Once inside the body, it inserts its genes and a small amount of protein
into a nerve cell. Then it works its way along, travelling toward the brain at
about a centimetre each day, and crossing from nerve cell to nerve cell. Once it
reaches the brain, the virus reproduces and spreads.
When viruses reach the salivary glands, they reproduce to
make millions of new viral particles, and this is the point at which the victim
becomes "mad", often biting and infecting other people, passing on
the virus-rich saliva. Once it is inside the nerve cells, the attacking virus
is safe from the vaccines, and the only other control is to amputate the bitten
limb, cutting off the virus' route to the brain as the limb is cut off.
In France, rabies is called La Rage, but it actually
produces two reactions among foxes: one of rage, when they become vicious and
bite, but other foxes go all cuddly, licking their den-mates — but in either
case, the infected fox is secreting rabies virus in its saliva, and infecting
those around it, whether by biting or licking. The name "hydrophobia"
reminds us that the victims feel painful spasms when they try to drink, and in
their delirium, become terrified of water.
It is quite possible that Edgar Allan Poe, master of the
Gothic, died of rabies, although doctors at the time believed he was drunk. One
of the key observations is that after he was found unconscious and taken to
hospital, he had trouble drinking water.
Poe had a history of alcohol and
opiate abuse, but according to his family, he had been 'clean' in the six
months before his death, and while doctors thought he was suffering delirium
tremens and offered him alcohol, he refused that as well. He went through
several bouts of improvement and relapse, which is typical of a death by rabies
in a human.
Poe loved cats, and may have contracted rabies from one. A
1994 case of a rabid kitten in New Hampshire led to medical costs of $1.1
million as 655 possible human contacts were treated. In other parts of the
world, though, bats spread rabies, rather than kittens, foxes, wolves or dogs,
and in France, before BSE, a vache
enragée was a rabid cow, not a mad cow.
The fact that bats may spread rabies made one Spanish
neurologist suggest that the vampire legend may come from a rabies epidemic in
the Balkans and Hungary from 1721 to 1728. Juan Gómez-Alonso was watching a
Dracula film when he noted some obvious similarities between vampires and what
happens in rabies, such as aggressiveness and hypersexuality.
By that time, the vampire bats of South America would have been well-known, but it is open to question what came first: in the linkage between bats and vampirism. A look at the often flaky and inexact Google ngram viewer reveals "vampire bat" made its first appearance in 1796: more research is needed here!
By that time, the vampire bats of South America would have been well-known, but it is open to question what came first: in the linkage between bats and vampirism. A look at the often flaky and inexact Google ngram viewer reveals "vampire bat" made its first appearance in 1796: more research is needed here!
Seven times as many men as women get rabies, and most
vampires are male. About a quarter of all rabid men attempt to bite others, and
rabid men often react to stimuli such as smells, water, and light with spasms
of the facial and vocal muscles that can cause hoarse sounds, bared teeth and
frothing at the mouth of bloody fluid — which may explain the use of garlic
against vampires.
Gómez-Alonso points out that rabies acts on the brain to
interfere with both sleep cycles and sexual behaviour: there are reports of
some "rabid patients who practiced intercourse up to 30 times in a
day", he wrote.
The vampire's fatal kiss may well reflect the presence of
the virus in saliva and other bodily secretions, and vampires are supposed to
come out at night, as a rabid person may well do. The association of bats and
werewolves with vampirism would then be an obvious consequence of the part bats
and wolves play in spreading rabies. Now what would Mr. Poe-the-horror-writer have done with
that?
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